Effect of the normalization template in statistical parametric mapping of PET scans
نویسندگان
چکیده
The standard template provided with the statistical software package SPM’99 was originally developed for O-H2O PET scans in resting condition with eyes closed. This template is commonly applied regardless of the tracer actually used in the scans being analyzed. This work studies the effect of three different normalization templates in the outcome of the statistical analyses of PET scans, as compared to a reference normalization. Results show that the use of the standard template in adverse conditions –different tracer, different cerebral condition– may introduce errors in the interpretation of the results of the statistical analysis.
منابع مشابه
Influence of the normalization template on the outcome of statistical parametric mapping of PET scans.
Spatial normalization is an essential preprocessing step in statistical parametric mapping (SPM)-based analysis of PET scans. The standard template provided with the SPM99 software package was originally constructed using (15)O-H(2)O PET scans and is commonly applied regardless of the tracer actually used in the scans being analyzed. This work studies the effect of using three different normali...
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